Feb 25, 2025

Pillr Health: A New Era of Innovation in 340B and Beyond

The healthcare landscape is evolving rapidly, and with it, the need for stronger, smarter partnerships has never been greater. Covered entities are navigating a time of uncertainty, where operational challenges, regulatory scrutiny, and resource constraints are putting unprecedented pressure on healthcare organizations. That’s why three industry leaders—RxStrategies, Hudson Headwaters 340B, and RPH Innovations—made a bold decision: to come together and form Pillr Health, a new entity designed to meet the moment and drive meaningful change.

Why Merge? Why Now?

Individually, RxStrategies, Hudson Headwaters 340B, and RPH Innovations had built strong reputations in their respective areas of expertise. Hudson Headwaters 340B, with its foundation in a network of Federally Qualified Health Centers (FQHCs), brought deep insights into the unique needs of safety-net providers. RxStrategies had established itself as a leader in technology-driven solutions for complex health systems. RPH Innovations, known for hands-on program management, provided personalized support to smaller covered entities.

Each company brought something valuable to the table, but the challenges facing the healthcare industry today require more than standalone expertise—they demand integration, efficiency, and a broader vision. By uniting under one organization, Pillr Health offers a more comprehensive approach, blending technology, compliance support, and program management to help clients thrive in an ever-changing environment.

More Than the Sum of Its Parts

At its core, Pillr Health is about building a foundation of strength for healthcare organizations. The merger isn’t just a consolidation of services—it’s an expansion of possibilities.

Enhanced Service Offerings: The combined capabilities of the three organizations allow Pillr Health to provide a wider range of solutions tailored to the distinct needs of healthcare providers. Whether it’s a large health system looking for cutting-edge technology or a small clinic in need of dedicated program management, Pillr Health has the expertise to deliver.

Streamlined Efficiency: In an industry where time is money—and often, the difference between compliance and risk—Pillr Health’s integrated approach eliminates inefficiencies, ensuring that clients receive faster, more effective support.

More Resources, Stronger Partnerships: With a larger pool of experts, an expanded network, and access to advanced technology, Pillr Health clients gain a level of support that is more comprehensive and effective than ever before.

Meet Our Team

Pillr Health is more than a new name—it represents a new way of supporting healthcare organizations. We invite you to meet our team and learn more about our solutions at the upcoming 340B Winter Coalition in San Diego, CA.

Recent Articles

Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services

Pillr Health is proud to announce a new national relationship with Sam’s Club.

Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.

This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.

Expanding Access, Empowering Growth

Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.

“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”

A Shared Commitment to the 340B Mission

At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.

Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services

Pillr Health is proud to announce a new national relationship with Sam’s Club.

Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.

This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.

Expanding Access, Empowering Growth

Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.

“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”

A Shared Commitment to the 340B Mission

At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.

Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services

Pillr Health is proud to announce a new national relationship with Sam’s Club.

Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.

This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.

Expanding Access, Empowering Growth

Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.

“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”

A Shared Commitment to the 340B Mission

At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.

Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims

Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.

Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims

Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.

Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims

Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.

Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities

Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).

This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.

Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.

We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities

Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).

This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.

Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.

We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities

Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).

This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.

Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.

We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.

Ready to get started?

Ready to get started?

The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.

The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.

Ready to get started?

The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.