Apr 24, 2025
Don’t Overlook the Importance of an HIN on Your Wholesale Accounts

Written by: Rachel Saari, Senior Director of Client Success



It’s easy to remember the days before 340B ESP, when setting up of a wholesale account was an easy and streamlined process. The Health Industry Number (HIN) was not something that was discussed very often prior to the manufacturer restrictions. The HIN is the unique identifier assigned to represent the specific relationship between the covered entity and pharmacy.
Presently, covered entities (CEs) need to not only be aware of each of their wholesaler accounts but also understand which 340B ID is associated with the account, and which manufacturers they have pricing for. The HIN plays a crucial role for CEs during this process. Whether you plan to make designations per site or are creating an ESP account for the first time, the HIN remains a consistent piece of the 340B program, across all CEs. If you know you need to purchase an HIN, don’t delay, it can take multiple weeks for the request to go through.
The HIN allows for efficient retrieval and verification of transaction records for the wholesaler and manufacturers. By using a common identifier, all parties can easily share and reconcile information, ensuring that 340B pricing is applied appropriately and that any discrepancies are promptly addressed. All 340B wholesaler accounts are required to have a HIN; without one, 340B pricing cannot be loaded to an account.
If you are unsure of what 340B ID and HIN are applied to your wholesale accounts, it is important to retrieve and maintain that information. This becomes especially important when working with ESP to apply designations, track pricing issues and ultimately support an effective and compliant 340B program.
Pillr Health is readily available to assist with any questions you may have.
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Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services
Pillr Health is proud to announce a new national relationship with Sam’s Club.
Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.
This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.
Expanding Access, Empowering Growth
Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.
“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”
A Shared Commitment to the 340B Mission
At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.
Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services
Pillr Health is proud to announce a new national relationship with Sam’s Club.
Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.
This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.
Expanding Access, Empowering Growth
Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.
“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”
A Shared Commitment to the 340B Mission
At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.
Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Pillr Health and Sam’s Club Partner to Launch a New Era of 340B Contract Pharmacy Services
Pillr Health is proud to announce a new national relationship with Sam’s Club.
Beginning January 1, 2026, Sam’s Club will use Highbridge, the 340B data-processing technology developed by Pillr Health, as its platform for managing all 340B contract pharmacy relationships.
This collaboration marks Sam’s Club’s first participation in the 340B program, creating new opportunities for Covered Entities to expand their networks and capture untapped program value. By leveraging Highbridge, Sam’s Club will deliver standardized, scalable, and compliant 340B services across its pharmacy network: ensuring consistency, transparency, and growth potential for partners nationwide.
Expanding Access, Empowering Growth
Through this partnership, Sam’s Club and Pillr Health are delivering a scalable technology framework that streamlines 340B operations and strengthens collaboration across the program’s national network.
“This partnership represents a pivotal step forward for both organizations,” said Skip Devanny, CEO of Pillr Health. “By combining Sam’s Club’s national reach with Pillr’s advanced technology, we’re enabling a new era of collaboration and value creation across the 340B ecosystem.”
A Shared Commitment to the 340B Mission
At its core, this partnership is about more than technology. It is about advancing the mission of 340B by expanding access, improving affordability, and empowering providers to reinvest in patient care.
Through this collaboration, Sam’s Club and Pillr Health are building a strong foundation for sustained 340B growth, helping safety-net providers strengthen compliance, increase savings, and extend their impact in the communities that need it most.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims
Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.
Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims
Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.
Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Expert Tip: Maximize 340B Savings by Manually Pulling in Rejected and Qualified Claims
Manually pulling in rejected and qualified claims in the TPA database is a critical step in capturing eligible 340B savings that may have been missed due to unmatched prescription data. Claims can fail to match automatically to an EMR (Electronic Medical Record) or ERX (Electronic Prescription) record due to discrepancies in provider documentation, timing issues, or data entry errors. By reviewing and manually adjudicating these claims, covered entities (CEs) can identify encounters that still meet 340B eligibility requirements but were not captured through automated matching. This practice ensures the entity maximizes its 340B benefit while maintaining program compliance.
Furthermore, this manual reconciliation process supports stronger audit preparedness and data integrity. By documenting the rationale for qualifying claims and ensuring proper linkage to eligible encounters, CEs can provide a defensible audit trail. It also helps identify patterns in rejected claims that may point to workflow or system issues, allowing for targeted improvements. Ultimately, consistently reviewing and processing unmatched claims manually helps optimize program performance while upholding the accuracy and accountability essential in 340B operations.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities
Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).
This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.
Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.
We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities
Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).
This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.
Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.
We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.

Pillr Health Achieves Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) Registration as well as NCPDP Setup, Strengthening Support for Covered Entities
Pillr Health is proud to share that we are now officially registered as a Medicare Transaction Facilitator (MTF) Third-Party Support Entity (TPSE) with the Centers for Medicare & Medicaid Services (CMS).
This milestone underscores Pillr Health’s role as a trusted partner in helping covered entities, pharmacies, and manufacturers navigate the evolving requirements of the Inflation Reduction Act (IRA) Maximum Fair Price (MFP) program.
Our technology and compliance platform is built to simplify complex processes—delivering seamless support across effectuation and reconciliation. In addition, Pillr Health has completed setup with the National Council for Prescription Drug Programs (NCPDP) as a Pharmacy Remit, Reconciliation, and Payment Vendor, further streamlining both operational and financial processes.
We remain committed to advancing solutions that empower healthcare organizations to thrive in today’s rapidly changing landscape.
Ready to get started?
Ready to get started?
The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.
The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.
Ready to get started?
The Pillr Health team is here to empower your 340B program, and beyond. Reach out at the link below.